My program of research seeks to provide a comprehensive account of the etiology of alcohol and other drug addiction in humans to bolster early identification and prevention efforts. Specifically, the C.R.E.A.M. (Clinical Research on Externalizing and Addiction Mechanisms) Lab focuses on disturbances in cognitive-affective processes across time that give rise to the emergence of substance use disorders (SUDs) and other forms of externalizing psychopathology. I have three complementary substantive areas in pursuit of the mechanisms of risk for addiction: (1) Understanding dispositional trait liabilities promotive of addiction, particularly as concerns the interplay between disinhibition and reward sensitivity, (2) bridging between- and within-subject mechanisms of risk for problematic consumption using ambulatory assessment techniques, and (3) evaluating and improving the generalizability and applicability of models of addiction to minoritized and socioeconomically-disadvantaged populations. To do this work, we use human neuroscientific methods (primarily electroencephalogram/event-related potentials [EEG/ERPs]), ambulatory assessment techniques (such as ecological momentary assessment), biometric (behavioral genetic) analyses, and a variety of statistical modeling approaches.
Bradford, D. E., Defalco, A., Perkins, E. R., Carbajal, I., Kwasa, J., Goodman, F. R., ... & Joyner, K. J. (in press). Whose signals are we amplifying? Towards a more equitable clinical psychophysiology. Clinical Psychological Science.
Perkins, E. R.*, Joyner, K. J.*, Patrick, C. J., Bartholow, B. D., Latzman, R. D., DeYoung, C. G., Kotov, R., Reininghaus, U., Cooper, S. E., Afzali, M. H., Docherty, A. R., Dretsch, M. N., Eaton, N. R., Goghari, V. M., Haltigan, J. D., Krueger, R. F., Martin, E. A., Michelini, G., Ruocco, A. C., Tackett, J. L., Venables, N. C., Waldman, I. D., & Zald, D. H. (2020). Neurobiology and the Hierarchical Taxonomy of Psychopathology: Progress toward ontogenetically informed and clinically useful nosology. Dialogues in Clinical Neuroscience, 22(1), 417-429.
Joyner, K. J., Bowyer, C.B., Yancey, J. R., Venables, N.C., Foell, J., Hajcak, G., Worthy, D., Bartholow, B., & Patrick, C. J. (2019). Blunted reward sensitivity and trait disinhibition interact to predict substance use problems. Clinical Psychological Science. 7(5), 1109-1124.
Joyner, K.J., Yancey, J.R., Venables, N.C., Burwell, S., Iacono, W.G., & Patrick, C.J. (2020). Using a Co-Twin Control design to evaluate alternative trait measures as indices of liability for Substance Use Disorders. International Journal of Psychophysiology, 148, 75-83.
Joyner, K. J., Daurio, A., Perkins, E. R., Patrick, C. J., & Latzman, R. D. (2021). The difference between disinhibition and impulsivity – And why it matters for clinical psychological science. Psychological Assessment, 33(1), 29–44.