Dopamine and Spatial Working Memory (012517C)
Michael Silver’s laboratory in the UC Berkeley School of Optometry is recruiting healthy adults to participate in a pharmacological study of dopamine and spatial working memory. Participation in this study involves viewing and responding to images presented on a computer screen. It consists of three sessions on different days, with each testing session lasting approximately 1-1.5 hours.
The first session is a screening session, and if you meet all eligibility criteria, you will be invited back for the additional sessions. Two of the subsequent sessions are pharmacology sessions. In each of these sessions, you will take a small dose of either placebo or levodopa, an FDA-approved drug that temporarily increases the brain’s dopamine levels. Because we must wait ~45 minutes after administering the medication to allow for absorption, the two pharmacology sessions last for about 2-2.5 hours each. During 45 minutes of waiting time, you would be free to do work, read, and use a computer, but you must remain in the lab. This time will count towards your compensation.
Compensation for study participation is $12/hour for all lab sessions in addition to a $50 bonus for successfully completing all of the sessions.
To be eligible, subjects must:
1. Be at least 18 years of age
2. Have normal (20/20) or corrected to 20/20 vision. If you have corrective contact lenses or glasses, please bring them with you to all sessions.
3. Not have asthma or other lung problems or have heart arrhythmia.
4. Not have recently used medications that affect dopamine levels (such as tolcapone, levodopa/carbidopa etc.)
5. Not be pregnant. Women of childbearing age will be provided with and asked to administer a home pregnancy test prior to each pharmacology session.
To participate or learn more, please contact Adeola Harewood at firstname.lastname@example.org
CPHS Approval # 2010-01-567